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Scientists at the Charlie Dunlop School of Biological Sciences at UC Irvine report that they have developed a powerful new tool, called Phollow, that lets scientists watch viral activity in the gut microbiome of living animals with unprecedented precision—down to ...

A study by researchers in the UC Irvine School of Medicine examines how our bodies activate defense mechanisms only in the presence of a virus, ensuring that uninfected, healthy cells are not harmed. Professor Rémi Buisson and graduate student Lavanya Manjunath talk about the findings here. The ...

“If you ever stop taking therapy, the virus can come roaring back,” says Matthew Marsden, a virologist at the University of California, Irvine. [Paul] Wender, Marsden, and others began to look at compounds that might be more effective. They turned ...

A research team from the University of California, Irvine has revealed a previously unknown mechanism that triggers an inflammatory immune response in cells when their DNA is damaged. This discovery deepens the understanding of a new type of cell signaling ...

UC Irvine researchers have developed a new understanding of the human antiviral defense response seen as pivotal for the development of new antiviral therapies. “Recognizing how cells recognize viral genomes and activate the signaling cascades that initiate antiviral defenses is crucial for ...