UC Irvine researchers have developed a new understanding of the human antiviral defense response seen as pivotal for the development of new antiviral therapies. “Recognizing how cells recognize viral genomes and activate the signaling cascades that initiate antiviral defenses is crucial for developing next-generation antiviral therapies,” said Rémi Buisson (above right, with biological chemistry graduate student Sunwoo Oh), an associate professor of biological chemistry in the School of Medicine.